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The purpose of this Funding Opportunity Announcement (FOA) is to provide opportunities for eligible small business concerns (SBCs) to submit NIH Small Business Innovation Research (SBIR) grant applications to develop interactive digital media science, technology, engineering and mathematics (STEM) resources that address student career choice and health and medicine topics for: (1) pre-kindergarten to grade 12 (P-12) students and pre- and in-service teachers and famlies or (2) Informal science education (ISE), i.e., outside the classroom resources for the general public. Interactive digital media (IDM) are defined as products and services on digital computer-based systems which respond to the user's actions by presenting content such as text, moving image, animation, video, audio, and video games. There is a large body of evidence that IDM technology has the potential to support learning in a variety of contexts from primary and secondary schools, to universities, adult education and workplace training. IDM is widely used to train, educate, and encourage behavioral changes in a virtual world format where progressive learning, feedback on success and user control are combined into an interactive and engaging experience. It is anticipated that this SBIR FOA will facilitate the translation of new or existing health and medicine-based, P-12 STEM curricula and museum exhibits into educational Interactive Digital Media STEM (IDM STEM) resources that will provide a hands-on, inquiry-based and learning-by-doing experience for students, teachers and the community.

The purpose of this Funding Opportunity Announcement (FOA) is to provide opportunities for eligible small business concerns (SBCs) to submit NIH Small Business Innovation Research (SBIR) grant applications to develop interactive digital media science, technology, engineering and mathematics (STEM) resources that address student career choice and health and medicine topics for: (1) pre-kindergarten to grade 12 (P-12) students, and pre- and in-service teachers and famlies ("Teachers") or (2) Informal science education (ISE), i.e., outside the classroom resources for the general public. Interactive digital media (IDM) are defined as products and services on digital computer-based systems which respond to the user's actions by presenting content such as text, moving image, animation, video, audio, and video games. There is a large body of evidence that IDM technology has the potential to support learning in a variety of contexts from primary and secondary schools, to universities, adult education and workplace training. IDM is widely used to train, educate, and encourage behavioral changes in a virtual world format where progressive learning, feedback on success and user control are combined into an interactive and engaging experience. It is anticipated that this SBIR FOA will facilitate the translation of new or existing health and medicine-based, P-12 STEM curricula and museum exhibits into educational Interactive Digital Media STEM (IDM STEM) resources that will provide a hands-on, inquiry-based and learning-by-doing experience for students, teachers and the community.

The objective of this Funding Opportunity Announcement (FOA) is to support the development of new and innovative long-acting systemic and non-systemic multipurpose prevention technologies (MPT). It supports development of MPTs that prevent HIV infection and pregnancy (hormonal and non-hormonal methods) in adolescent and young women. Applications for MPT development may involve pharmacokinetic (PK), pharmacodynamic (PD), safety and, drug-drug interactions (DDI) studies. It also encourages biobehavioral and behavioral/social studies to identify MPT end user preferences factors (look, feel, effectiveness, safety and duration of action) and other behavioral/social factors that could promote increased MPT use in adolescent and young women.

The purpose of this Notice of Funding Opportunity (NOFO) is to provide opportunities for eligible small business concerns (SBCs) to develop interactive digital media (IDM) biomedical science resources for pre-college students and teachers.

Overview: The Bureau of International Narcotics and Law Enforcement Affairs of the U.S. Department of State announces an open competition for organizations to submit applications to carry out a project providing a community-based solution to counter gang recruitment in selected communities of Trinidad and Tobago (TT). Countering the spread of criminal gangs is an INL Priority goal under mission goal 1, “Enhanced Citizen Security and Rule of Law’, objective 1.2 ‘Institutions support at-risk communities to address the underlying drivers of crime, gang involvement and violent extremism’, Sub Objective 1.2.1 ‘TT expands youth development and diversion programs to disincentivize gang involvement, strengthens juvenile justice systems, and improve relationships between law enforcement and at-risk communities’ Criminal gang activities drive violent crime and homicides in TT. This undermines public safety, negatively impacting livelihood, consumer confidence, foreign investment, and the ability of every citizen to enjoy peaceful and friendly communities. Lack of sustainable economic opportunities creates a climate for recruiting vulnerable youth into criminal gangs, leading to a decrease in the productive capacity of the young adult population between the ages of 18-35, especially males. Youth between the ages of 10 and 18 are more susceptible to societal and cultural ‘push’ factors, and ‘pull’ factors within the gang itself. Familial factors such as parental drug and alcohol abuse, violence at home, and parental criminality or gang membership are amongst the strongest predictors or delinquency and gang involvement. Community ‘push’ factors linked to joining gangs include social disorganization, availability of firearms, access to drugs and cultural norms supporting gang behavior. Youth may be pushed towards gang culture to resist structural violence they experience in their own community. In addition, the presence of pre-existing gangs correlates strongly with furth